Scientific Leadership in IEF

CEPharm 2007

1.    Analysis of Glycosylated Type II Interleukin-1 Receptor (IL-1R) by Imaged Capillary Isoelectric Focusing (i-cIEF)
Mei Han
Analytical Sciences, Amgen, Inc., Seattle, Washington

2. Advantages of Performing icIEF Analysis in cGMP Environment
Li-Ping Hsieh¹, Päivi Albaiti¹, Catherine Bilodeau¹, Elena Vasilyeva¹,
Damian Houde², Tyler Carlage², Zoran Sosic², Joseph Molon¹
Quality Control Chemistry¹ and Analytical Development²,
Biogen Idec, Inc., Cambridge, MA, USA

3.    Imaged Capillary Isoelectric Focusing (iCIEF) – Transition from Slab Gel and Ion Exchange LC to Analytical Miniaturization for Protein Analysis
Jinping Liu, John Capodici, Nataliya Afonina, and Michael Grace
Bioanalytical Sciences, Protein Therapeutic Development,
Bristol-Myers Squibb, Hopewell, NJ 08534, USA

4.    Method Development Using Imaged Capillary IsoelectricFocusing (iCIEF) Techniques for Therapeutic Biologics
John Capodici, Jinping Liu, Nataliya Afonina, and Michael Grace
Bioanalytical Sciences, Protein Therapeutic Development,
Bristol-Myers Squibb, Hopewell, NJ 08534, USA

5. Method Development for cIEFCollaboration Project: Carrier Ampholyteand Additive Selection for the IgGSample
Jiaqi Wu
Convergent Bioscience Ltd, Toronto, Ontario, Canada M8Z 2L8

6.    Investigation of the Linearity and Stability of the pH Gradient Formed by Carrier Ampholytes with Whole Column Detection cIEF
Tiemin Huang, Jiaqi Wu
Convergent Bioscience Ltd, Toronto, Ontario, Canada M8Z 2L8

7. Imaged cIEF As A Research Tool For Monoclonal Antibody Characterization and Development
Zhang M, Yim K
Pharmaceutical Sciences, Favrille Inc.

8.    Instrument-to-Instrument Variability of Convergent Bioscience iCE280
James McElroy, David A. Michels, Paula Kong and Oscar Salas-Solano
Late Stage Analytical Development, Genentech. Inc,
1 DNA Way, South San Francisco, CA 94080

9. Implementation of Imaged Capillary Isoelectric Focusing in Quality Control
Zara Safarian
QC Scientist, Genentech Inc.

10. Imaged cIEF - The Best Solution for Complex Biomolecules
Carmelina Crisci, L. Grimaldi, Katia Minari, Mara Rossi,
& Carlo Emanuele Giartosio
Protein Chemistry Dept.,
Industria Farmaceutica Serono - An Affiliate of MerckSerono,
Ardea (Rome) Italy

For more presentations, please go to www.ciefforum.com/WCBP07TechDocs/ and
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